Quantification and technique development to reduce ano-rectal toxicity in prostate radiotherapy.
Recruiting
- Conditions
- prostate cancerprostate carcinoma1003858810036958
- Registration Number
- NL-OMON33176
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Biopsy proven prostate carcinoma.
Localized prostate carcinoma (cT1-3N0M0)
Written informed consent.
Exclusion Criteria
Previous treatment for this tumour, other than neo-adjuvant androgen suppression therapy.
Distant metastases
Contra-indications for radiotherapy (Morbus Crohn, ulcerative colitis, severe diverticulitis.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Subjective complaints, based on questionnaires.<br /><br>Anal pressures and rectal compliance.<br /><br>Amount and severity of telangiectasias to the rectal and sigmoid mucosa.<br /><br><br /><br>In addition, the course of these parameters over 2 years and their correlation,<br /><br>and the correlation to the doses to the rectum and anal canal. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable.</p><br>