Effectiveness of a Procedure for Previously Failed Glaucoma Surgery

Completed

• Conditions: Glaucoma

• Registration Number: NCT00347789
• Lead Sponsor: Glaucoma Research & Education Group

Brief Summary

Transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to treat cases with a previously failed trabeculectomy. We will investigate approximately 100 consecutive cases with follow up of up to 9 years. We anticipate that this procedure is an effective, safe, and appropriate option for successful glaucoma treatment.

Detailed Description

The healing process after filtering surgery for glaucoma may cause an unsuccessful outcome for the trabeculectomy procedure. In order to control the rising intraocular pressure due to the failed trabeculectomy, medications may be restarted and/or filtering surgery may need to be repeated. Our primary research showed that transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to control this situation.

This retrospective study will follow over 100 patients from May 1997 to May 2006. This long-term follow up will help assess the future role of this technique in glaucoma practices.

Study Timeline

• Study Start: 1997-05
• Status Verified: 2006-06
• Study Completion: 2006-06
• Study First Submitted: 2006-06-30
• Study First Submitted QC: 2006-06-30
• Last Update Submitted: 2006-06-30
• Study First Posted: 2006-07-04
• Last Update Posted: 2006-07-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Diagnosis of glaucoma
• Failed filtering procedures- defined as intraocular pressure exceeded target pressure thus inducing possible further optic nerve damage

Exclusion Criteria

• Needling combined with other ocular surgical or laser treatments

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Glaucoma Center of San Francisco; 🇺🇸 San Francisco, California, United States