NCT00558688已完成不适用
A Photodynamic Therapy for Treatment of Actinic Keratoses
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Visual assessment of lesions
研究概览
简要总结
The purpose of this study is to compare the efficacy of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light vs absence of treatment for actinic keratoses.
详细描述
This study seeks to evaluate the efficacy of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light vs. absence of treatment for actinic keratoses
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than or equal to 18 years
- •Have a t least 4 nonhypertrophic AK lesions on the body
- •The subjects are in good health
- •The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate to the investigator
排除标准
- •Subjects who are pregnant or lactating
- •Subjects with a history of cutaneous photosensitivity or porphyria, hypersensitivity to porphyrins, or photodermatosis
- •Subjects with use of photosensitizing drugs within 1 week of study start
- •Subjects with use of topical medications such as corticosteroids, alpha-hydroxyacids or retinoids 2 weeks before study entry
- •Subjects with systemic steroid therapy within 4 weeks before study entry
- •Subjects who received previous treatment of target AKs
- •Subjects with systemic treatment with chemotherapeutic agents, masoprocol (Actinex), immunotherapy, or retinoids within 2 months of study entry
- •Subjects with prior history of hypersensitivity reactions to lidocaine
- •Subjects who are unable to understand the protocol or to give informed consent
结局指标
主要结局
Visual assessment of lesions
时间窗: 4 weeks
次要结局
- Patient subjective assessment and Safety(4 weeks)
研究者
Murad Alam
Professor in Dermatology, Otolaryngology-Head and Neck Surgery, and Surgery
Northwestern University
研究点 (2)
Loading locations...
相似试验
Unknown
3 期
Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder DermisC. AcnesPhototherapyPostoperative InfectionArthroscopic Rotator Cuff RepairShoulder SurgeryNCT04636242Rothman Institute Orthopaedics120
已完成
不适用
Treatment of Actinic Keratoses With Photodynamic Therapy Using Sunlight Versus Red LightActinic KeratosesNCT00432224Bispebjerg Hospital28
撤回
不适用
Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic KeratosesActinic KeratosisNCT00814528University of Chicago
招募中
不适用
Photodynamic therapy with topical 5-aminolevulinic acid for the treatment of skin cancersskin cancersJPRN-UMIN000004329Department of Plastic and Reconstructive Surgery, Osaka City University, Graduate School of Medicine10
招募中
4 期
Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and PreventionActinic KeratosesNCT03642535Shanghai Dermatology Hospital300