Lingual Tonsil Hypertrophy Grading and Its Relation to Sociodemographic Factors and Clinical Symptoms
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Lingual tonsil enlargement grade on videolaryngoscopy
研究概览
简要总结
The aim of this research was to evaluate the lingual tonsil hypertrophy (LTH) grading of patients with dysphagia using videolaryngoscopy and determine the relation of LTH grades to sociodemographic factors and clinical symptoms.
详细描述
Two groups of people were interviewed during this research - the LTH group and the control group - a total of 100 subjects. The first group was comprised of 50 individuals, who visited the otorhinolaryngologist at Lithuanian University of Health Sciences hospital, regarding dysphagia, and were diagnosed with LTH during endoscopy. The second group consisted of 50 healthy individuals without dysphagia, who did not have enlarged lingual tonsils during assessment using videolaryngoscopy. All subjects filled out the questionnaires, composed of RSI (Reflux Symptom Index) and DSQ (Dysphagia Screening Questionnaire) questionnaires, validated and verified for use in Lithuania, together with a questionnaire created specifically for this research for gathering sociodemographic data.
The LTH grade of all subjects was determined using DelGaudio and Friedman grading systems.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Consent for participating in the research
- •No cognitive disorders or mental illnesses
- •Complaining about difficulty swallowing (research group)
- •Enlarged lingual tonsils on videolaryngoscopy (research group)
- •Generally healthy, no complaints of swallowing disorders (control group)
- •Normal-sized lingual tonsils (control group)
排除标准
- •Refusal to participate in the research
- •Younger than 18 and older than 80 years old
- •Serious mental or cognitive conditions
结局指标
主要结局
Lingual tonsil enlargement grade on videolaryngoscopy
时间窗: At baseline
Lingual tonsil enlargement grade was assessed using DelGaudio (2008) and Friedman (2015) grading systems during videolaryngoscopy. According DelGaudio severity of LTH was assessed as: grade 0- lingual tonsils are not enlarged; 1- the lingual tonsils are prominent but not in full contact with the epiglottis or obscuring the valleculae; 2- the lingual tonsils obscure the view of the valleculae and are fully in contact with the epiglottis; 3- the lingual tonsils fill the valleculae and partially or fully obscure the view of the epiglottis. Friedman grading system consists of 0 to 4 scale: 0- complete absence of lymphoid tissue; 1- lymphoid tissue scattered over tongue base; 2- lymphoid tissue covering entirety of tongue base with limited vertical thickness; 3- significantly raised lymphoid tissue covering entirety of the tongue base, approximately 5 to 10 mm in thickness; 4- lymphoid tissue rising above the tip of the epiglottis, 10 or more mm in thickness.
次要结局
- Sociodemographic factors: age(At baseline)
- Sociodemographic factors: gender(At baseline)
- Sociodemographic factors: body mass index (BMI)(At baseline)
- Sociodemographic factors: gastrointestinal diseases(At baseline)
- Sociodemographic factors: history of fibroesophagogastroduodenoscopy (FEGDS) findings(At baseline)
- Sociodemographic factors: occupation and employment status(At baseline)
- Sociodemographic factors: health behaviors(At baseline)
- Sociodemographic factors: previous tonsillectomy(At baseline)
- Sociodemographic factors: use of antacids(At baseline)
- Sociodemographic factors: allergic diseases(At baseline)
- General health status(At baseline)
- Reflux Symptom Index questionnaire(At baseline)
- Dysphagia Screening Questionnaire(At baseline)
- Symptom severity(At baseline)
研究者
Nora Siupsinskiene
Professor medical doctor of otorhinolaryngology
Lithuanian University of Health Sciences