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临床试验/CTRI/2025/01/079433
CTRI/2025/01/079433已完成不适用

Assessment of salivary bacterial load in children aged 6-12 years following Herbal, Chlorine dioxide and probiotic based mouthrinsing using Oratest: An Invivo study

Dr. Shaik Salma1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年2月10日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60
试验地点
1
主要终点
Caries activity test using Oratest

研究概览

简要总结

Oral hygiene practices intervening with plaque formation are crucial in preventing dental caries. Raising concerns of toxicity with conventional mouthwash usage led to the search for biologically safe mouth rinsing agents in children. The present study aims to evaluate the efficacy of Herbal (Botanical Oral rinse) and Stabilized Chlorine Dioxide (ClO2) mouthwash in reducing salivary bacterial load in children aged 6-12 years. Prior to intervention, caries risk activity will be evaluated through a simple chair-side Oratest as a baseline data. The children will then be instructed to rinse the allocated mouthwash once daily for 60 sec for 14 days and fill out the supplied checklist. The assessment of all the parameters will be repeated after 14 days of intervention and the values will be subjected to statistical analysis.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant and Investigator Blinded

入排标准

年龄范围
6.00 Year(s) 至 12.00 Year(s)(—)
性别
All

入选标准

  • Children with DMFT score 2-
  • Children with no history of antibiotics or probiotics in any form in the past three months.

排除标准

  • Medically compromised children 2) Children with history of systemic allergies and diseases.
  • Children using any prosthetic/orthodontic appliances.

结局指标

主要结局

Caries activity test using Oratest

时间窗: Time taken for change in color of the milk prior and after use of mouthwash for 14 days will be assessed through Oratest.

次要结局

  • To evaluate and compare the anti-cariogenic efficacy of Herbal, Stabilized Chlorine dioxide and Probiotic mouthwash in children aged 6-12 years.(14 days of intervention)

研究者

发起方
Dr. Shaik Salma
申办方类型
Other [Self supported study]
责任方
Principal Investigator
主要研究者

Shaik Salma

GITAM dental college and Hospital

研究点 (1)

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