Effects of Aerobic Training During Hemodialysis on Exercise Tolerance in End Stage Renal Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Effects of aerobic training during hemodialysis on exercise tolerance and VO2 kinetics in end stage renal disease patients
研究概览
简要总结
The investigators raised the hypothesis that exercise training would be associated with improvement in exercise tolerance and VO2 kinetics in hemodialysis patients.
详细描述
End-stage renal disease (ESRD) is associated with several hemodynamic and peripheral muscle abnormalities which could slow the kinetics of O2 uptake(VO2)and diminished tolerance to incremental exercise. Although previous studies have shown that aerobic training is able to accelerate VO2 kinetics in several disease populations, little is known if these positive findings are also applicable to hemodialysis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The sample included end stage renal disease patients undergoing hemodialysis, three times per week totaling 12h weekly, for at least 6 months in the Nephrology Unit at the University Hospital of the Federal University of Juiz de Fora, State of Minas Gerais, Brazil. No patient had been involved in any kind of exercise training in the preceding 6 months
排除标准
- •unstable angina;
- •uncontrolled arrhythmia;
- •uncompensated heart failure;
- •uncontrolled hypertension (systolic blood pressure ≥ 200 mmHg and/or diastolic blood pressure ≥ 120 mmHg);
- •diabetes mellitus;
- •severe respiratory diseases;
- •acute infection;
- •severe renal osteodystrophy;
- •neurological or musculoskeletal disturbances
结局指标
主要结局
Effects of aerobic training during hemodialysis on exercise tolerance and VO2 kinetics in end stage renal disease patients
时间窗: 3 months
Before and after the intervention or control periods, the participants were submitted to an incremental work rate test and, two days apart, to a constant work rate test to the limit of tolerance.
次要结局
未报告次要终点