Bright light therapy to improve sleep and quality of life in children with acute lymphoblastic leukaemia

Not Applicable

Recruiting

• Conditions: Acute Lymphoblastic Leukaemia; Sleep Disorders; Fatigue; Quality of Life; Cancer - Children's - Leukaemia & Lymphoma

• Registration Number: ACTRN12616000187448
• Lead Sponsor: isa Walter

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Children 3 to 9 years of age
Undergoing maintenance treatment for acute lymphoblastic leukaemia
White cell count less than 50,000 cells per microliter
Favourable cytogenetics, i.e. no extreme hypodiploidy with < 44 chromosomes/cell; MLL gene rearrangement; Philadelphia chromosome positivity; Internal amplification of chromosome 21
No cerebrospinal disease

Exclusion Criteria

Children who are blind
Have a history of diagnosed retinal problems
On photo-sensitive medication, such as azole anti-fungal medication (risk of photosensitivity
On medications which alter/induce sleep
On psychotropic medications
Non-English speaking and/or non-English speaking parents
Have pre-existing developmental disabilities
Have epilepsy or migraines
Wear tinted glasses
Are in foster care or with documented protective services involvement.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composite outcome of sleep quantity and quality, using a combination of actigraphy, sleep diary and the Tayside Children’s Sleep Questionnaire.<br><br>[Comparing the five days before light therapy to the last five days of the second cycle of maintenance treatment];Quality of life using the PedsQL - Cancer module and the Mood and Feelings Questionnaire[Comparing the five days before light therapy to the last five days of the second cycle of maintenance treatment];Daytime sleepiness using the Modified Epworth Sleepiness Scale [Comparing the five days before light therapy to the last five days of the second cycle of maintenance treatment]