ISRCTN16462783CompletedUnknown
Pilot Feasibility Study of Cognitive control in cocaine dependence: A multi-centre randomized controlled trial to pilot targeting craving for cocaine using memory reconsolidation techniques
Kings College London0 sites30 target enrollmentStarted: August 28, 2015Last updated:
Trial Snapshot
- Phase
- Unknown
- Status
- Completed
- Sponsor
- Enrollment
- 30
Study Overview
Brief Summary
2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29478874 results
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Adult (between 18 and 50 years old)
- •2. English speaking
- •3. Current diagnosis for cocaine dependence (ICD-10)
- •4. Self-reported regular cocaine use (weekly) and cocaine-positive UDS during screening
- •5. Motivation to reduce or quit cocaine use
Exclusion Criteria
- •1. Current diagnosis of post-traumatic stress disorder (DSM-5)
- •2. Current non-medical benzodiazepine or harmful alcohol use (>50 units per week men; >35 units women)
- •3. Use of heroin or cocaine in the 24 hours before first CRF session
- •4. Clinically significant on-going medical problems that might make participation unsafe
- •5. Acute housing instability
- •6. Uncontrolled serious psychiatric illness
- •7. Significant neuro-cognitive functioning (<18, Montreal Cognitive Assessment)
- •8. Pregnant or breast feeding
- •9. Current enrollment in an addiction treatment related clinical research study
Investigators
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