Pilot Feasibility Study of Cognitive Control in Cocaine Dependence

Not Applicable

Completed

• Conditions: Cocaine dependence; Mental and Behavioural Disorders

• Registration Number: ISRCTN16462783
• Lead Sponsor: Kings College London

Brief Summary

2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29478874 results

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-08-28
• Study Completion: 2018-02-02
• Last Update Posted: 3 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Adult (between 18 and 50 years old)
2. English speaking
3. Current diagnosis for cocaine dependence (ICD-10)
4. Self-reported regular cocaine use (weekly) and cocaine-positive UDS during screening
5. Motivation to reduce or quit cocaine use

Exclusion Criteria

1. Current diagnosis of post-traumatic stress disorder (DSM-5)
2. Current non-medical benzodiazepine or harmful alcohol use (>50 units per week men; >35 units women)
3. Use of heroin or cocaine in the 24 hours before first CRF session
4. Clinically significant on-going medical problems that might make participation unsafe
5. Acute housing instability
6. Uncontrolled serious psychiatric illness
7. Significant neuro-cognitive functioning (<18, Montreal Cognitive Assessment)
8. Pregnant or breast feeding
9. Current enrollment in an addiction treatment related clinical research study

Study & Design

• Study Type: Interventional
• Study Design: Not specified