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Clinical Trials/NCT06454656
NCT06454656
Recruiting
Not Applicable

A "MOtor Learning Based Intervention for Lower Extremities (MOBILE)" to Target Walking Performance in Ambulant Children With Cerebral Palsy: A Feasibility Study

Royal College of Surgeons, Ireland2 sites in 1 country14 target enrollmentAugust 12, 2024

Overview

Phase
Not Applicable
Intervention
MOBILE
Conditions
Cerebral Palsy
Sponsor
Royal College of Surgeons, Ireland
Enrollment
14
Locations
2
Primary Endpoint
Fidelity to Intervention Protocol
Status
Recruiting
Last Updated
18 days ago

Overview

Brief Summary

The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.

The main questions we look to answer are:

  1. Do the children/teens tolerate the therapy and feel that it is helpful?
  2. Do the parents/ families feel the therapy helps and is easy to commit to?
  3. Do the children/teens complete all their therapy sessions and assessments as planned?

The participants will trial the therapy for 30 hours over 6 weeks and will perform assessments before and after to see if they meet their goals. They will also be interviewed to see how they felt about the therapy when they finish.

Detailed Description

The therapy being trialed in this study uses motor learning theory to try and improve or change walking patterns to improve the child/teen's walking goal. Therapy will target their own walking goal and they can choose the format of their therapy as long as they complete 30 hours of which 24 hours must be in the clinic within a 6 week period.

Registry
clinicaltrials.gov
Start Date
August 12, 2024
End Date
June 1, 2027
Last Updated
18 days ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Royal College of Surgeons, Ireland
Responsible Party
Principal Investigator
Principal Investigator

Catriona O'Shaughnessy

Professional Doctorate Scholar

Royal College of Surgeons, Ireland

Eligibility Criteria

Inclusion Criteria

  • Primary diagnosis of Cerebral Palsy (GMFCS Levels I-III)
  • Has a specific walking related goal
  • Has capacity to follow instruction
  • Has a primary caregiver who can support a home program

Exclusion Criteria

  • Has had surgery within 6 months of intervention start date
  • Has had botox/ baclofen within 3 months of intervention start date
  • Has a dual diagnosis that impacts ability to follow instruction
  • Has a significant cognitive impairment

Arms & Interventions

Intervention

Participants will undergo 30 hours of therapy over 6 weeks in format of their choosing. A minimum of 24 hours must be completed in clinic with the rest made up of home program.

Intervention: MOBILE

Outcomes

Primary Outcomes

Fidelity to Intervention Protocol

Time Frame: Duration of study 2 years

Checklist to measure extent of motor learning principles included in sessions

Adherence to Intervention

Time Frame: Duration of study 2 years

Percentage of total hours practiced/ planned dose (30 hours)

Feasibility of Outcome Measures (Participant)

Time Frame: Duration of study 2 years

Participant experience of outcomes captured by semi-structured interviews.

Acceptability of Intervention

Time Frame: Duration of study 2 years

Semi-structured interviews of participants and parents to capture acceptability of intervention using Framework of acceptability

Retention

Time Frame: Duration of study 2 years

Percentage of recruited participants at final follow up

Adverse Events

Time Frame: Duration of study 2 years

Measured as Yes or No with description

Recruitment Rate

Time Frame: rolling recruitment over 1.5 years

Percentage of eligible numbers recruited

Time taken to complete Outcome Measures

Time Frame: Duration of study 2 years

Measured in Minutes

Feasibility of Outcome Measures (Assessor)

Time Frame: Duration of study 2 years

Assessor experience of outcomes captured by semi-structured interview.

Secondary Outcomes

  • Gait Outcome Assessment List(baseline, upon completion of intervention (2-6 weeks) and 3 month follow up, rolling through duration of study 2 years)
  • 10 meter self-selected walking speed(baseline, upon completion of intervention (2-6 weeks) and 3 month follow up, rolling through duration of study 2 years)
  • Modified timed up and go(baseline, upon completion of intervention (2-6 weeks) and 3 month follow up, rolling through duration of study 2 years)
  • 6 minute walk test(baseline, upon completion of intervention (2-6 weeks) and 3 month follow up, rolling through duration of study 2 years)
  • ankle and knee Range of motion(baseline, upon completion of intervention (2-6 weeks) and 3 month follow up, rolling through duration of study 2 years)
  • Child Health Utilities Index CHU-9D(baseline, upon completion of intervention (2-6 weeks) and 3 month follow up, rolling through duration of study 2 years)

Study Sites (2)

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