MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Completed

• Conditions: Behçet's Disease

• Registration Number: NCT01780363
• Lead Sponsor: Cukurova University

Brief Summary

Background: Genetics is suggested to play a critical role in the development of Behçet's disease (BD). Shared phenotypic features requires an approach to the differential diagnosis from periodic febrile syndromes particularly from mevalonate kinase deficiency related diseases. We planned to study for evaluating the frequency of mutations and their clinical significance in mevalonate kinase gene in Turkish patients with Behçet's disease.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-01
• Study Start: 2011-01
• Primary Completion: 2011-12
• Study First Submitted: 2013-01-29
• Study First Submitted QC: 2013-01-29
• Last Update Submitted: 2013-01-29
• Study First Posted: 2013-01-31
• Last Update Posted: 2013-01-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Behçet patients

Exclusion Criteria

• Diagnosis of periodic fever syndromes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of mevalonate kinase frequency in Behçet disease	One year

Secondary Outcome Measures

Name	Time	Method
Mevalonate kinase gene and clinical correlations in Behçet's disease	One year

Trial Locations

Locations (2)

Didem Arslan Tas; 🇹🇷 Adana, Turkey

Cukurova University; 🇹🇷 Adana, Turkey