Seroepidemiological Study of SARS-CoV-2 (COVID-19) Infection in Population Subgroups in the State of São Paulo

Completed

• Conditions: COVID; SARS-CoV 2
• Interventions: Diagnostic Test: Serological test; Diagnostic Test: Nasopharyngeal Swab; Diagnostic Test: Oropharyngeal Swab

• Registration Number: NCT04408014
• Lead Sponsor: Butantan Institute

Brief Summary

Seroepidemiological Study of SARS-CoV-2 Infection in Population Subgroups in the State of São Paulo

Detailed Description

This is a cross-sectional study to estimate the prevalence of antibodies against SARS-CoV-2 is different population subgroups in the State of São Paulo

Study Timeline

• Study First Submitted: 2020-05-22
• Study First Submitted QC: 2020-05-27
• Study First Posted: 2020-05-29
• Study Start: 2020-06-01
• Primary Completion: 2020-07-15
• Study Completion: 2020-07-30
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-14
• Last Update Posted: 2024-02-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18901

Inclusion Criteria

• All potential volunteers invited to participate in the study.

Exclusion Criteria

• All potential eligible participants, but who do not show interest in participating in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CPP - Butantan Penitentiary Progression Center	Oropharyngeal Swab	Participants of the CPP - Butantan Penitentiary Progression Center
CHSP - Penitentiary System Hospital Center	Oropharyngeal Swab	Participants of the CHSP - Penitentiary System Hospital Center
SABE (Health, Wellness and Aging)	Serological test	Participants of the SABE Project (Health, Wellness and Aging)
ILPI - Long-Term Care Institution for the Elderly	Nasopharyngeal Swab	Residents of the Long-Term Care Institution for the Elderly of Botucatu
ILPI - Long-Term Care Institution for the Elderly	Oropharyngeal Swab	Residents of the Long-Term Care Institution for the Elderly of Botucatu
HC-USP	Nasopharyngeal Swab	Home contacts of health professionals diagnosed with COVID-19 at the Hospital of Clínic of Medicine School of the University of São Paulo
CPP - Butantan Penitentiary Progression Center	Serological test	Participants of the CPP - Butantan Penitentiary Progression Center
CORAS	Serological test	Refugees living in the city of São Paulo
CORAS	Oropharyngeal Swab	Refugees living in the city of São Paulo
CPP - Butantan Penitentiary Progression Center	Nasopharyngeal Swab	Participants of the CPP - Butantan Penitentiary Progression Center
CHSP - Penitentiary System Hospital Center	Serological test	Participants of the CHSP - Penitentiary System Hospital Center
SABE (Health, Wellness and Aging)	Nasopharyngeal Swab	Participants of the SABE Project (Health, Wellness and Aging)
ICR-USP - Children's Institute of HCFMUSP	Nasopharyngeal Swab	Home contacts of children and adolescents diagnosed with COVID-19, attended at the Children's Institute of HCFMUSP
HC-USP	Oropharyngeal Swab	Home contacts of health professionals diagnosed with COVID-19 at the Hospital of Clínic of Medicine School of the University of São Paulo
Hemocenter	Serological test	Blood Donors of the Pró-Sangue Hemocenter Foundation of São Paulo
CORAS	Nasopharyngeal Swab	Refugees living in the city of São Paulo
CHSP - Penitentiary System Hospital Center	Nasopharyngeal Swab	Participants of the CHSP - Penitentiary System Hospital Center
ILPI - Long-Term Care Institution for the Elderly	Serological test	Residents of the Long-Term Care Institution for the Elderly of Botucatu
ICR-USP - Children's Institute of HCFMUSP	Serological test	Home contacts of children and adolescents diagnosed with COVID-19, attended at the Children's Institute of HCFMUSP
HC-USP	Serological test	Home contacts of health professionals diagnosed with COVID-19 at the Hospital of Clínic of Medicine School of the University of São Paulo
SABE (Health, Wellness and Aging)	Oropharyngeal Swab	Participants of the SABE Project (Health, Wellness and Aging)
ICR-USP - Children's Institute of HCFMUSP	Oropharyngeal Swab	Home contacts of children and adolescents diagnosed with COVID-19, attended at the Children's Institute of HCFMUSP

Primary Outcome Measures

Name	Time	Method
Prevalence of antibodies against SARS-CoV-2 through serological testing	1 month	IgM and IgG antibodies against SARS-CoV-2
Frequency of participants with a positive RT-PCR test result for SARS-CoV-2	1 month	Positive RT-PCR test result for SARS-CoV-2

Trial Locations

Locations (1)

Avenida Vital Brasil 1500; 🇧🇷 Sao Paulo, Brazil