Comparison of Morphine Versus Dexmedetomidine as Adjuvant to Intrathecal Hyperbaric Bupivacaine on the Duration of Anaesthesia in Infraumbilical Surgeries
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare the sensory and motor characteristics between morphine
研究概览
简要总结
In this study I will be administering 2.5 mcg dexmedetomidine with 0.5% hyperbaric bupivacaine 15mg to one group and 150 mcg morphine with 0.5% hyperbaric bupivacaine 15 mg to another group of patients who are undergoing infraumbilical surgeries and who are fulfilling our inclusion and exclusion criteria. The primary aim of this study is to compare duration of anaesthesia between two groups and time for first rescue analgesia. Adverse effects if any will be observed and treated accordingly.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anesthesiologists(ASA) Physical Status Grade I and Grade II patients. Patients within BMI range of 18.5kg.
- •24.9 Patients willing to give informed consent to participate in the study.
排除标准
- •Patients on long term treatment with any opioids and α2 agonist Patients taking α receptor antagonists, calcium channel blockers, angiotensin converting enzyme inhibitors or on any kind of analgesics Patients who are pregnant.
结局指标
主要结局
To compare the sensory and motor characteristics between morphine
时间窗: 12 hours
and dexmedetomidine as adjuvant to intrathecal 0.5% hyperbaric
时间窗: 12 hours
bupivacaine in spinal anaesthesia for infraumbilical surgeries.
时间窗: 12 hours
次要结局
- To compare cardiorespiratory changes between the groups(To compare adverse events between the groups)
研究者
Dr Santhosh M C B
Mandya Institute of Medical Sciences