A investigation of the correlation between the distribution of local anesthetic and the sensory area of modified thoracoabdominal nerves block through perichondrial approach (M-TAPA): a volunteer study
- Conditions
- healthy adult male volunteers
- Registration Number
- JPRN-UMIN000051586
- Lead Sponsor
- Hokkaido University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- 10
Not provided
1. History of asthma 2. Allergy or hypersensitivity to research-related drugs 3. Patients with a history of trauma or surgery involving the muscular layer in the thoracoabdominal area 4. Patients who already have sensory abnormality in the thoracoabdominal area 5. Those who are unable to undergo MRI imaging due to claustrophobia, presence of metal in the body, etc. 6. Those who weigh less than 50 kg or have a BMI of 25 or more. 7. Patients with anatomical abnormalities at the puncture sites that may pose a risk 8. Patients with severe renal, hepatic, or hemostatic functional disorders, etc. 9. Patients taking antithorombotic drugs 10. Other subjects who are deemed inappropriate as research subjects by the principal investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The correlation between the sensory area and subcutaneous drug distribution confirmed by pinprick test and MRI at 60 and 120 min after
- Secondary Outcome Measures
Name Time Method The adverse events associated with M-TAPA The duration of Analgesia