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临床试验/CTRI/2023/05/053020
CTRI/2023/05/053020尚未招募2/3 期

A Comparative Clinical Evaluation on the Role of Panch Lavan Ghrit Nasya and Vachadi Potli Ghranam with or without Internal Goghritpan in Vataja Pratishyaya (Allergic Rhinitis)

Dr Himanshi1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2023年1月7日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Decrease in the symptoms like Sneezing, Rhinorrhea, Stuffiness of nose

研究概览

简要总结

The increasing prevalence of Allergic Rhinitis globally is a matter of concern. Worldwide, allergic rhinitis affects between 10% to 30% of the population. Worldwide sensitization (IgE antibodies) to foreign protiens in the environment is present in upto 40% of the population. About 20-30% of Indian population suffer from at least one allergic disease where allergic rhinitis alone constitutes about 55% of all allergies. This region of Haryana is Semi-arid & dusty. Allergic Rhinitis is quite common in this area. Patients of Vataja Pratishyaya(Allergic Rhinitis) after having treatment from various Many treatment modalities are explained in Allopathic science like Corticosteroids, Anti-Allergic drugs, Inhalers, Antihistamines etc. but none of them are totally effective in curing the disease as well as preventing its recurrence, more over they have their own side effects like Rhinitis medicamentosa, fungal growth due to Topical steroids etc. . Hence there is a need for more effective, safe, treatment modality which is especially  beneficial in chronic cases to treat this problem from grass root level. Nasya Karma is considered as the main Shodhana therapy to expel Doshas from the Shira. Both Bringhan and Rechan Nasya are very beneficial for removing the Doshas from the body especially in chronic cases as the Doshas are lodged in different parts of Urdhavjatru. Moreover, in Vataja Pratishyaya, as there is Vimarga gamana of Vata Dosha, Panchlavan Ghrit Nasya with Vachadi Potli Ghranam does Shira shodhana and Vata Anulomana and hence it can be beneficial in this disease. In order to promote Shamana effect, Goghrit is selected for internal administration in patients suffering from Vataja Pratishyaya (Allergic Rhinitis). Hence this study entitled “A Randomized Comparative Clinical Evaluation on the Role of Panchlavan Ghrit Nasya and Vachadi Potli Ghranam with or without Internal Goghritpan in Vataja Pratishyaya (Allergic Rhinitis)†is selected for providing a better relief without any recurrence and in order to find an effective solution to the above problem for curing the disease from its root cause.

For this study total 60 patients will be taken, 30 in each group. First group will be given Panchlavan Ghrit Nasya and Vachadi Potli Ghranam with internal Goghritpa( 10-20 ml, Twice a day) administration for 30 days and other group will be given Panchlavan Ghrit Nasya and Vachadi Potli Ghranam without administration of internal Goghritpan for 30 days period, after that three follow ups will be done at 50th, 60th and 90th day and changes will be noted.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Not Applicable

入排标准

年龄范围
16.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients presenting with signs and symptoms of Vataja Pratishyaya mentioned in Ayurvedic Classics and Allergic Rhinitis according to Allopathic science.
  • 2.Patients willing to participate in the study.
  • 3.Patient of either sex.

排除标准

  • 1.Patients having history of systemic disease as Diabetes Mellitus, Hypertension, Hypothyroidism.
  • 2.Patients suffering from gross deviation of nasal septum, nasal tumours, adenoid hyperplasia, nasal polyps etc.
  • 3.Pregnant women.
  • 4.Patients not fit for Nasya therapy and Ghritpana.

结局指标

主要结局

Decrease in the symptoms like Sneezing, Rhinorrhea, Stuffiness of nose

时间窗: 90 days

次要结局

  • To See change in AEC, ESR levels(To decrease the grade of severity of disease)

研究者

发起方
Dr Himanshi
申办方类型
Other [self]

研究点 (1)

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