It is a study done on patients undergoing general anaesthesia to study effect of precurarisation with succinylcholine on succinylcholine induced fasciculations and myalgia.The study is done to assess the efficacy of cisatracurium,rocuronium and placebo.
Phase 3
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: M958- Other specified acquired deformities of musculoskeletal system
- Registration Number
- CTRI/2023/03/050956
- Lead Sponsor
- DR GURULINGAPPA A PATI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients undergoing elective surgery under general anesthesia
2.Patients age between 18-60 years
3.Patients who fulfill American Society of Anesthesiology category I and II
Exclusion Criteria
1.Cardiovascular, pulmonary or metabolic diseases
2.Morbid obesity
3.Neuromuscular disease
4.Anticipated airway difficulties
5.Intraocular hypertension
6.Malignant hyperthermia
7.Caesarean section
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Study the efficacy of cisatracurium and rocuronium pretreatment in preventing <br/ ><br>succinylcholine induced fasciculations. <br/ ><br>2.Study the efficacy of cisatracurium and rocuronium pretreatment in preventing postoperative myalgia in post-anesthesia care unit(PACU)Timepoint: 1.Study the efficacy of cisatracurium and rocuronium pretreatment in preventing <br/ ><br>succinylcholine induced fasciculations at baseline. <br/ ><br>2.Study the efficacy of cisatracurium and rocuronium pretreatment in preventing postoperative myalgia in post-anesthesia care unit(PACU) for 2 hours.
- Secondary Outcome Measures
Name Time Method 1.Study the efficacy of cisatracurium and rocuronium pretreatment in preventing postoperative myalgia at 24hoursTimepoint: From 2 hours post-operatively till 24hours post-operatively.