Long-term Outcome of Triple-vessel Coronary Artery Disease Underwent Three Different Strategies (LOTUS)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
- Enrollment
- 10000
- Locations
- 1
- Primary Endpoint
- All-cause mortality
- Last Updated
- 10 years ago
Overview
Brief Summary
The study is to determine the long-term outcome of patients with coronary triple vessels disease (TVD) in the real world of China, by three different treatment strategies: percutaneous coronary intervention (PCI), Coronary artery bypass graft (CABG) or optimal medication therapy (OMT).
Detailed Description
About 10,000 participants will be enrolled into this retrospective study. Study coordinators will include both men and women over the age of 18 who had angiographic proved triple-vessel disease in a 15 years long-term. Detailed procedural data will be obtained by the study coordinator and local principal investigator. These data will be entered into the electronic data capture system. Participants will have telephone follow-up interviews conducted by the centralized follow-up center at Fuwai Hospital.
Investigators
Lei Song
MD
Chinese Academy of Medical Sciences, Fuwai Hospital
Eligibility Criteria
Inclusion Criteria
- •Subject has coronary angiography confirmed triple-vessel disease.
- •Subject is ≥ 18 years of age at the time of inclusion.
- •Subject is willing to comply with all protocol-required follow-up evaluation (patient will be followed during 1 month after hospital to assess any complications and clinical status).
Exclusion Criteria
- •Subject is participating in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation.
- •Female subjects with a positive quantitative or qualitative pregnancy test, in accordance with hospital policy.
- •Subjects with no way contact by telephone for follow-up.
Outcomes
Primary Outcomes
All-cause mortality
Time Frame: Through study completion, an average of 5 year
The mortality due to any cause
Secondary Outcomes
- Myocardial infarction(Through study completion, an average of 5 year)
- Major adverse cardiac and cerebrovascular event(Through study completion, an average of 5 year)
- Stroke(Through study completion, an average of 5 year)
- Repeat revascularization(Through study completion, an average of 5 year)