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BAY 77-1931 Long-term Extension From Phase II Study

Phase 2
Completed
Conditions
Hyperphosphatemia
Interventions
Drug: BAY 77-1931
Registration Number
NCT00769496
Lead Sponsor
Bayer
Brief Summary

A long-term study of BAY77-1931 (lanthanum carbonate) for hyperphosphatemia in patients undergoing hemodialysis

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
145
Inclusion Criteria
  • Undergoing hemodialysis 3 times per week for chronic renal failure for the previous 3 consecutive months at least
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Exclusion Criteria
  • Pre-dialysis serum phosphate levels of 10.0mg/dL during the washout period
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Arm 1BAY 77-1931-
Primary Outcome Measures
NameTimeMethod
Changes in pre-dialysis serum phosphate levelsEvery 4 weeks
Secondary Outcome Measures
NameTimeMethod
Achievement rate of the target predialysis serum phosphate levels (3.5 mg/dL and 5.5 mg/dL)Every 4 weeks
Changes in corrected serum calcium levelEvery 4 weeks
Changes in the product of serum calcium and phosphateEvery 4 weeks
Changes in serum intact-PHT levelsEvery 4 weeks
Changes in bone metabolism markersEvery 4 weeks
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