A real world study for Yi-Qi Huo-Xue prescription in the treatment of angina pectoris of coronary heart disease

Oriental Hospital, Beijing University of Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. Consistent with the diagnosis of coronary heart disease angina pectoris, with one of the following evidence:
•(1) There is a clear history of old myocardial infarction;
•(2) Coronary angiography, suggesting at least one coronary stenosis, and lumen stenosis >=50%;
•(3) CTA suggested stenosis of the main vascular lumen >= 50% (or above moderate stenosis);
•2. Angina pectoris attacks >=2 times per week;
•3. Meet the diagnostic criteria of qi deficiency and blood stasis;
•4. Aged 30-75 years;
•5. Voluntarily sign the informed consent.

•1. Coronary revascularization was performed within 60 days;
•2. Use any preparation of traditional Chinese medicine (such as proprietary Chinese medicine, Chinese medicine granule, etc.) in the recent month;
•3. Acute myocardial infarction occurred in recent month;
•4. Patients with one of the following diseases:
•(1) Patients with high blood pressure after hypertension and antihypertensive drug treatment (systolic blood pressure >= 180mmHg, diastolic blood pressure >=100mmHg);
•(2) Severe arrhythmia (atrial fibrillation with rapid ventricular response, atrial flutter, paroxysmal ventricular tachycardia, etc.), pulmonary heart disease, rheumatic heart disease, myocarditis, cardiomyopathy, aortic dissection, pulmonary embolism and other serious diseases;
•5. Chest pain symptoms related to hyperthyroidism, cervical spondylosis, gallbladder heart syndrome, gastroesophageal reflux disease or hiatal hernia, neurosis, climacteric syndrome, etc.;
•6. The upper limit of serum alanine transaminase or serum creatinine >2 times the normal reference value.
•7. Severe hematological diseases.
•8. Malignant tumor;
•9. Women of child-bearing age who are pregnant or breast-feeding or who are required to have children;
•10. Mental illness or cognitive dysfunction;
•11. Allergic to the test drug;
•12. Have participated in other clinical trials within the recent month.

发起方

Oriental Hospital, Beijing University of Chinese Medicine