Sub-acute Exercise Following Sport-Related Concussion
- Conditions
- Sport-related Concussion
- Interventions
- Behavioral: Exercise
- Registration Number
- NCT03575455
- Lead Sponsor
- Florida State University
- Brief Summary
Determine the safety and efficacy of sub-maximal aerobic exercise during the subacute phase of recovery following sport-related concussion.
- Detailed Description
The main objective of the proposed study is to determine is exercise during the first 3-7 days following a sport-related concussion can help improve the systemic neurological dysfunction following a concussion while examining the safety and efficacy of a 20-minute, low- to moderate-intensity (40-60% of HRMAX) controlled treadmill aerobic exercise as a therapeutic modality to improve cardiovascular, psychological, vestibulo-ocular, autonomic, and cognitive function.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Not provided
- physical limitation prohibiting treadmill walking
- reports dizziness or lightheadedness
- presents with any contraindication for exercise participation as defined by American College of Cardiology (ACC), American Heart Association (AHA), or American College of Sports Medicine (ACSM) guidelines.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Exercise Exercise Concussed participants will participate in a single 20' bout of treadmill walking at either 40% or 60% of the age-predicted HRmax. Healthy participants will participate in a single 20' bout of treadmill walking at either 40% or 60% of the age-predicted HRmax.
- Primary Outcome Measures
Name Time Method Clinical Recovery The number of days from injury to full medical clearance up to 365 days. 80% of adolescent athletes fully recover in less than 28 days. Clinical recovery is defined as the duration from the time of injury to the time a patient has received full clearance without restriction.
- Secondary Outcome Measures
Name Time Method Blood Pressure (SBP & DBP) SBP & DBP will be captured for 10 minutes before, 20 minutes during, and after 25 minutes post "treatment". SBP \& DBP will be recorded with an automated auscultatory BP system
Concussion Symptoms Symptoms will be captured for 10 minutes before, 20 minutes during, and after 25 minutes post "treatment". All 22 symptoms from the Post-concussion symptom scale (PCSS) as measured on a Likert scale from 0 (not present) to 6 (severe)
Exercise Bout Completion Rates Completion will be determined and recorded at the end of the acute 20 minute treatment. The rate of completion will be defined as the ability for the participant to finish the "treatment" without early termination.
Heart rate variability (HRV) HRV will be captured for 10 minutes before, 20 minutes during, and after 25 minutes post "treatment". The RR Interval will be extracted from the heart rate monitoring system.
Ocular Dysfunction The King-Devick (K-D) will be administered before and within 5 minutes after the acute 20 minute "treatment" Improvements in ocular dysfunction will be defined as a decrease in errors or reading time
Rating of Perceived Exertion (RPE) RPE will be captured for 10 minutes before, 20 minutes during, and after 25 minutes post "treatment". Borg's CR-15 will be utilized to quantifying perceived intensity of exercise
Incidence of Persistent Postconcussion symptoms >28 days The duration in days will be calculated from the day injury to the day full clearance up to 1 year. Persistent symptoms duration will be categorized as either ≤28 days or \> 28 days.
Vestibular Dysfunction The Vestibular / Ocular Motor Screening (VOMS) will be administered before and within 5 minutes after the acute 20 minute "treatment" Improvements in vestibular dysfunction will be defined as a decrease in symptom provocation or pretest symptom reporting
Trial Locations
- Locations (1)
Tallahassee Orthopedic Clinic
🇺🇸Tallahassee, Florida, United States