Efficacy of a topical formulation of Myrtus communis L. for patients with chronic anal fissure

Fasa University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2018年5月21日

适应症

试验速览

暂无简介。

•the age over 18 years to maximum 70 years;The presence of symptoms of chronic anal fissure (including: bleeding, pain, or both,) for more than 6 weeks;the presence of anal fissure in physical exam;the appearance of horizontal fibers of internal anal sphincter and or sentinel anal tag or hypertrophic papilla;;written informed consent for inclusion.

•sensitivity and allergy to Myrtus communis L. or Diltiazem or Acetaminophen ;anal or rectal surgeries during 12 weeks ago;inflammatory bowel disease;others anal disease including abscess,fistula,moderate or severe eczema around anus or mass(pile);Immunodeficiency diseases;A history of diseases that require continued consumption of analgesics;any cardio-vascular or cerebro-vascular disease;consumption of calcium channel blochers drugs in general or current use of them in threatment of fissure;history of radiotherapy to pelvic region;anal fibrosis or fixed stenosis;history of important renal ,liver,neurologic,hematologic and psychiatry diseases;history of stool incontinency;history of chronic constipation or constipation during 4 weeks ago( 2 episodes defication or less weekly with straining or dense stool passing);pregnancy and lactation;alcohol and opium addiction;inability to cooperate in completing forms(mood disorders or language problems)

发起方

Fasa University of Medical Sciences