The Beijing Adult Dry Eye Cohort Study

Active, not recruiting

• Conditions: Dry Eye

• Registration Number: NCT06621446
• Lead Sponsor: Beijing Tongren Hospital

Brief Summary

To investigate the prevalence of dry eye in adults in Beijing, and explore the extremely dangerous factors of dry eye in adults in Beijing through two years follow-up, and establish a prediction model of dry eye; On this basis, the prevention and treatment strategy of dry eye disease suitable for Chinese people is put forward, and its actual effect is verified.

Detailed Description

Specifically, it is planned to carry out cluster random sampling in Jianguomen community, Yongdingmenwai community, and Jiaodaokou community in Dongcheng District, Beijing, and select adults over the age of 18 to enter the queue for observation; In order to ensure the accuracy of the prevalence survey, people with mobility difficulties or mental problems are not excluded. The subjects will be examined by ophthalmology and OSDI questionnaire to determine whether these people have dry eyes. Then the prevalence of dry eye would be expolored. Then through one-year and two-year follow-up, the incidence would be explored.

Study Timeline

• Study Start: 2023-07-15
• Primary Completion: 2023-08-31
• Study First Submitted: 2024-09-23
• Study First Submitted QC: 2024-09-28
• Status Verified: 2024-10
• Study First Posted: 2024-10-01
• Last Update Submitted: 2024-10-07
• Last Update Posted: 2024-10-09
• Study Completion: 2025-08-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

• Aged 18 or above, resident population of sample community, able to complete dry eye examination, informed consent signed

Exclusion Criteria

• Mental illness, mobility difficulties, can not participate in follow-up

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of Dry eye	two years	The incidence of dry eye is the primary outcome, and will be calculated by number of newly developed dry eye cases divided by total number of those who didn\'t have dry eye in last year.; The presence of dry eye will be measured relying on the following examinations: questionnaire, tear break-up time examination

Secondary Outcome Measures

Name	Time	Method
Prevalence of Dry Eye	one year	The prevalence of dry eye is the secondary outcome. The prevalence will be defined as number of dry eye cases, divided by total participants. Dry eye will be measured relying on questionnaire and tear break-up time examination.

Trial Locations

Locations (1)

Beijing; 🇨🇳 Beijing, Beijing, China