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Clinical Trials/NCT00158119
NCT00158119
Completed
Phase 3

Ameliorating Disability Through Power Training

National Institute on Aging (NIA)1 site in 1 country160 target enrollmentJuly 2001

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Mobility Limitations
Sponsor
National Institute on Aging (NIA)
Enrollment
160
Locations
1
Primary Endpoint
Leg power
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.

Detailed Description

Muscle power, a separate physical attribute from strength, is an important determinate of physical functioning in the elderly, for example in avoiding impending falls, rising from a chair, and climbing stairs. Muscle power, which declines with aging at a different rate than strength, has been shown in previous studies to improve through power training utilizing specially designed exercise equipment. However, weighted vest exercise could provide an acceptable, low cost, readily accessible alternative. The hypotheses being tested in this study are: 1) weighted vest exercise will improve lower extremity power when compared to age matched controls in a standardized progressive resistance training program; 2) improvements in lower extremity power enhance functional performance as shown by improved gait velocity, stair climbing, and chair rise time; and 3) weighted vest exercise in impaired older adults will improve self-reported function and disability. One hundred sixty-four men and women ages 65 and older, with some physical limitation but able to climb stairs independently, will be randomized to one of two 16-week exercise programs. The intervention group will participate in a weighted vest exercise protocol, consisting of chair-based and stair-climbing exercise, while the control group will participate in a standardized progressive resistance training program. Participants in both programs will meet three times per week for 30-60 minutes per session, for a total of 16 weeks, at a research exercise gym, and will be under the direct supervision of research staff.

Registry
clinicaltrials.gov
Start Date
July 2001
End Date
September 2007
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
National Institute on Aging (NIA)

Eligibility Criteria

Inclusion Criteria

  • Community dwelling men and women aged 65 or older
  • Ability to provide informed consent
  • Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time
  • Score of 24 or greater on the Folstein mini-mental status exam
  • Exhibit independent stair-climbing ability

Exclusion Criteria

  • Unstable acute or chronic disease
  • Neuromusculoskeletal impairment interfering with independent stair climbing
  • Abdominal aortic aneurysm
  • Exertional angina
  • History of ventricular arrhythmia
  • Inguinal or abdominal hernia
  • Symptomatic valvular heart disease

Outcomes

Primary Outcomes

Leg power

leg strength

mobility

endurance

balance measured at baseline, 8 weeks, and 16 weeks

Secondary Outcomes

  • Disability

Study Sites (1)

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