Fluid Optimization in Liver Surgery

Completed

• Conditions: Cancer of Liver

• Registration Number: NCT01627808
• Lead Sponsor: Catholic University of the Sacred Heart

Brief Summary

The purpose of this study is to analyze hemodynamic changes, in patients undergoing liver resection, through the Vigileo/FloTrac system.

Detailed Description

To reduce bleeding, hepatectomies are performed with low central pressure (CVP) combined with extrahepatic control flow.

This management can lead hemodynamic instability and reduction in oxygen delivery so an advanced monitoring should be used.

This study analyzes hemodynamic changes, in patients undergoing liver resection, through the Vigileo/FloTrac system.

Study Timeline

• Study Start: 2011-09
• Primary Completion: 2012-02
• Study Completion: 2012-05
• Status Verified: 2012-06
• Study First Submitted: 2012-06-22
• Study First Submitted QC: 2012-06-25
• Last Update Submitted: 2012-06-25
• Study First Posted: 2012-06-26
• Last Update Posted: 2012-06-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• ASA I-III

Exclusion Criteria

• Cirrhosis
• systolic ventricular contractility or diastolic relaxation alterations
• ischemic or valvular diseases
• absence of sinusal rhythm
• impaired renal function

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stroke volume variation	at time of surgery	Evaluation of changes in Stroke Volume Variation from Vigileo/FloTrac system during liver resection.

Secondary Outcome Measures

Name	Time	Method
Stroke volume variation	at the end of surgery	Evaluation of changes in Stroke Volume Variation at the end of liver resection, during fluid optimization.

Trial Locations

Locations (1)

Catholic University of Sacred heart; 🇮🇹 Rome, Italy