Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct Stones：a Long-term Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 104
- 试验地点
- 1
- 主要终点
- the recurrence rate of EBD stones
研究概览
简要总结
The management of coexisting intrahepatic bile duct (IBD) and extrahepatic bile duct (EBD) stones is complicated and requires a multidisciplinary approach. The long-term clinical outcomes of patients initially treated with endoscopic retrograde cholangiopancreatography (ERCP) EBD stone extraction remain unclear. Investigators conducted a retrospective study of patients with coexisting IBD and EBD to investigate the long-term impact of ERCP on the incidence of recurrent EBD stones and to identify risk factors of recurrence.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •non-gastrointestinal tract reconstruction patients with coexisting IBD and EBD stones who underwent ERCP between July 2008 and December 2020 at Xijing Hospital in China
排除标准
- •patients with benign or malignant EBD strictures
- •sclerosing cholangitis
- •suspected choledochal cysts
- •liver cirrhosis
- •parasitic liver diseases
- •long-term biliary drainage with biliary stents or percutaneous tubes
- •without a definitive IBD stone or with a diagnosis of liver calcification as determined by imaging review
- •medical records or follow-up information was unavailable
结局指标
主要结局
the recurrence rate of EBD stones
时间窗: up to 2 years
Stone recurrence was defined as new EBD stone formation beyond 3 months after complete initial clearance.
次要结局
未报告次要终点
研究者
Yanglin Pan
Professor
Air Force Military Medical University, China