Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct Stones

Recruiting

• Conditions: Intrahepatic Bile Duct Stone; Choledocholithiasis

• Registration Number: NCT06041113
• Lead Sponsor: Air Force Military Medical University, China

Brief Summary

The management of coexisting intrahepatic bile duct (IBD) and extrahepatic bile duct (EBD) stones is complicated and requires a multidisciplinary approach. The long-term clinical outcomes of patients initially treated with endoscopic retrograde cholangiopancreatography (ERCP) EBD stone extraction remain unclear. Investigators conducted a retrospective study of patients with coexisting IBD and EBD to investigate the long-term impact of ERCP on the incidence of recurrent EBD stones and to identify risk factors of recurrence.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-09
• Study Start: 2023-09
• Study First Submitted: 2023-09-05
• Study First Submitted QC: 2023-09-14
• Last Update Submitted: 2023-09-14
• Study First Posted: 2023-09-18
• Last Update Posted: 2023-09-18
• Primary Completion: 2024-07
• Study Completion: 2024-07

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 104

Inclusion Criteria

• non-gastrointestinal tract reconstruction patients with coexisting IBD and EBD stones who underwent ERCP between July 2008 and December 2020 at Xijing Hospital in China

Exclusion Criteria

• patients with benign or malignant EBD strictures
• sclerosing cholangitis
• suspected choledochal cysts
• liver cirrhosis
• parasitic liver diseases
• long-term biliary drainage with biliary stents or percutaneous tubes
• without a definitive IBD stone or with a diagnosis of liver calcification as determined by imaging review
• medical records or follow-up information was unavailable

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the recurrence rate of EBD stones	up to 2 years	Stone recurrence was defined as new EBD stone formation beyond 3 months after complete initial clearance.

Trial Locations

Locations (1)

Xijing Hospital of Digestive Diseases; 🇨🇳 Xi'an, Shaanxi, China