Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.
- Conditions
- Pelvi Ureteric Junction Obstruction or Ureteral Stricture
- Interventions
- Procedure: buccal mucosal graft to repair iatrogenic PUJO
- Registration Number
- NCT04503330
- Lead Sponsor
- Cairo University
- Brief Summary
Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.
- Detailed Description
A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter.
after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis.
Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
- any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture
- elderly patients unfit for general anaesthesia.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Patients with iatrogenic PUJO buccal mucosal graft to repair iatrogenic PUJO patients with iatrogenic PUJO or long segment ureteric stricture disease for safety and efficacy of using buccal graft for repair
- Primary Outcome Measures
Name Time Method Number of Participants with patent renal pelvis and ureter after surgery. 3 months 3 months after surgery Diuretic renography will be done to judge patency of the pelvis and ureter and resolution of hydronephrosis
- Secondary Outcome Measures
Name Time Method