Using Buccal Mucosal Graft as an Augmention Graft for Complex Cases of Iatrogenic Pelviureteric Junction Obstruction and Long Segment Ureteric Stricture Disease.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pelvi Ureteric Junction Obstruction or Ureteral Stricture
- Sponsor
- Cairo University
- Enrollment
- 20
- Primary Endpoint
- Number of Participants with patent renal pelvis and ureter after surgery.
- Last Updated
- 5 years ago
Overview
Brief Summary
Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.
Detailed Description
A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter. after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis. Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.
Investigators
Ahmed Abozamel
principal investigator urologist
Cairo University
Eligibility Criteria
Inclusion Criteria
- •any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture
Exclusion Criteria
- •elderly patients unfit for general anaesthesia.
Outcomes
Primary Outcomes
Number of Participants with patent renal pelvis and ureter after surgery.
Time Frame: 3 months
3 months after surgery Diuretic renography will be done to judge patency of the pelvis and ureter and resolution of hydronephrosis