MedPath

A Phase IIb/III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Dose- Range Finding Clinical Trial of MK-0941 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insuli

Phase 1
Conditions
Treatment of Type 2 Diabetes
MedDRA version: 9.1 Level: LLT Classification code 10012601 Term: Diabetes mellitus
Registration Number
EUCTR2008-002121-36-FR
Lead Sponsor
aboratoires Merck Sharp & Dohme-Chibret
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Not specified
Target Recruitment
550
Inclusion Criteria

Patient is 21 to 70 years old and currently on a stable dose of insulin for Type 2 Diabetes.
HbA1c at visit 4 ( randomization) HbA1c =7.5% and =11.0%
BMI > 20kg/m² and <43 kg/m² at visit 1 ( screening)
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Patient has any history of Type 1 Diabetes; patient is on a weight loss program and is not in the maintenance phase, or patient is taking a weight loss medication (e.g., orlistat, sibutramine, rimonabant) within 8 weeks of Visit 1;patient has undergone surgery within 30 days prior to Visit 1 or has planned major surgery.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath