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Clinical Trials/CTRI/2022/08/044782
CTRI/2022/08/044782
Completed
N/A

COMPARATIVE EVALUATION OF BONE REGENERATION WITH L-PRF , AMNIOTIC MEMBRANE AND SIMVASTATIN USING CBCT AFTER ENDODONTIC SURGERY : A RANDOMIZED CLINICAL TRIA

Dr Niharika Singh0 sites42 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
Health Condition 1: K045- Chronic apical periodontitisHealth Condition 2: K046- Periapical abscess with sinusHealth Condition 3: K047- Periapical abscess without sinusHealth Condition 4: M275- Periradicular pathology associatedwith previous endodontic treatmentHealth Condition 5: K048- Radicular cyst
Sponsor
Dr Niharika Singh
Enrollment
42
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
March 1, 2024
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
Dr Niharika Singh

Eligibility Criteria

Inclusion Criteria

  • Age group 20\-40 yrs.
  • Subjects having CBCT\- periapical score 4 \& 5\. ( Diameter of periapical radiolucency \>4\-8 mm \& \>8mm respectively ) . This new PAI score was based on CBCT (CBCT\-PAI) and introduced in 2008 by Estrela et al.\[17]
  • Failed re\-RCT with persistent sign and symptoms of infection eg. Swelling, sinus, pus discharge etc.
  • Subjects requiring periapical root end surgery involving anterior teeth.
  • Subjects with sufficient motivation and capable of reporting back to the clinic for follow up visits.

Exclusion Criteria

  • Subjects diagnosed with diabetes mellitus or any systemic diseases which is likely to influence healing
  • Patients requiring re\-apicoectomy.
  • Smokers and alcoholics.
  • Patients with bone disorders.
  • Patients with anomalies of blood and immune system.
  • Patients with malignant tumors and/ or on cancer therapy.
  • Pregnant females.

Outcomes

Primary Outcomes

Not specified

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