Association of Lecithin-cholesterol Acyltransferase Activity and Low-density Lipoprotein Heterogeneity with Atherosclerotic Cardiovascular Risk: A Pilot Longitudinal Study
Not Applicable
- Conditions
- The criterion for patient registration was the presence of one or more risk factors for atherosclerosis.
- Registration Number
- JPRN-UMIN000033228
- Lead Sponsor
- Department of Cardiology, Nihon University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
Not provided
Exclusion Criteria
hepatic dysfunction (alanine aminotransferase and aspartate aminotransferase more than 2 times the upper limit of the normal values), known malignant disease, refusal to provide consent for participation in the study, or the diagnosis of acute coronary syndrome within 3 months prior to the study, and/or serum TG 400 mg/dL.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endo point was to evaluate the association of the absolute change in LCAT activity with the change in LDL particle size, using a multilogistic regression analysis
- Secondary Outcome Measures
Name Time Method