The effect of Portulaca oleracea capsule on knee osteoarthritis
- Conditions
- Knee osteoarthritis.
- Registration Number
- IRCT20190406043175N5
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Initial symptomatic osteoarthritis in at least one knee by clinical or radiological criteria ACR (American College of Rheumatology) is approved
Lack of proper adherence to routine drug treatment (meloxicam tablets) for at least two weeks before the study
Score higher than 30 at baseline VAS scale
The intra-articular injection of hyaluronic acid in the three months before the start of the study
The 4-week treatment with oral corticosteroids before the start of the study
Patients with a history of deep vein thrombosis
Active liver or renal disease and malignancies
Secondary osteoarthritis or suspected
Patients treated with hormonal drugs
Patients treated with anticoagulation drugs
Patients with a history of ischemic or hemorrhagic stroke
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Early intervention, four weeks after the intervention, eight weeks after intervention. Method of measurement: Western Ontario and McMasters Universities Osteoarthritis Index (Womac) questionnaire and Visual Analog Scale (VAS) scale.;Joint stiffness. Timepoint: Early intervention, four weeks after the intervention, eight weeks after intervention. Method of measurement: (Womac) questionnaire and (VAS) scale.;Physical performance. Timepoint: Early intervention, four weeks after the intervention, eight weeks after intervention. Method of measurement: (Womac) questionnaire and (VAS) scale.
- Secondary Outcome Measures
Name Time Method