EUCTR2014-003469-10-NL
Active, Not Recruiting
Phase 1
The application of contrast-enhanced ultrasound to facilitate thrombolysis in patients with acute peripheral arterial occlusions. - MUST Trial
VU University Medical Center0 sites20 target enrollmentJuly 9, 2015
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- VU University Medical Center
- Enrollment
- 20
- Status
- Active, Not Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Men and women older than 18 years and younger than 85 years old
- •Patients with a maximum of 7 weeks complaints due to lower limb ischemia due to
- •thrombosed/occluded iliofemoral, femoropopliteal or femorocrural native arteries or femoropopliteal or
- •femorocrural venous or prosthetic bypass grafts
- •Anatomic suitability duplex ultrasound in case of iliac occlusion
- •Patients fit for thrombolysis i.e. with acute lower limb ischemia class I and IIa according to the
- •Rutherford classification (see attachment II)
- •Patients understand the nature of the procedure and provide written informed consent before enrolment
- •in the study
- •Are the trial subjects under 18? no
Exclusion Criteria
- •Patients with clinical complaints of acute lower limb ischemia due to thrombosis of the iliofemoral, femoropopliteal or femorocrural native arteries, or femoropopliteal or femorocrural venous or prosthetic bypass grafts more than 7 weeks
- •Patients with iliac occlusions anatomically not suitable for duplex ultrasound
- •Patients with thrombosed popliteal aneurysms
- •Patients with contra\-indications for the administration of antiplatelet therapy, anticoagulants or thrombolytics
- •Recent (less than 6 weeks) ischemic stroke, cerebral bleeding or myocardial infarction
- •Patients with recent (less than 6 weeks) surgery
- •Severe hypertension (diastolic blood pressure greater than 110 mm Hg, systolic blood pressure higher than 200 mm Hg)
- •Current malignancy or severe comorbid condition with a life expectancy of less than 6 months
- •Patients with uncorrected bleeding disorders (gastrointestinal ulcer, menorrhagia, liver failure)
- •Women with child\-bearing potential not taking adequate contraceptives or currently breastfeeding
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
N/A
The use of ultrasound in the therapy of patients with blocked arteries of the lower limb.peripheral arterial occlusions, peripheral vascular disease, vascular disease, lower limb occlusive disease, acuut perifeer vaatlijden, acute vaatocclusieNL-OMON27379VU University Medical Center20
Completed
Phase 2
The application of contrast-enhanced ultrasound to facilitate thrombolysis in patients with acute peripheral arterial occlusions.NL-OMON46851Vrije Universiteit Medisch Centrum20
Completed
N/A
Contrast enhansed ultrasound in evalution of in-stent prtrusion after carotid stenting.Stroke,Carotid stenosisJPRN-UMIN000024727Department of Stroke Medicine,Kawasaki Medical School20
Completed
N/A
sefulness of contrast-enhanced ultrasonography with Sonazoid for diagnosis and liver function assessment for Non-alcoholic steatohepatitis (NASH).JPRN-UMIN000014400Faculty of Medicine, University of Tsukuba, Medical Science60
Recruiting
N/A
sefulness of contrast-enhanced ultrasonography with Sonazoid for Head and Nedk LesioHead and neck tumorJPRN-UMIN000011731Yamaguchi University Hospital200