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临床试验/NCT06042868
NCT06042868尚未招募不适用

Effect of Implementing Emergency Nursing Protocol About Obstructive Anuria and Oliguria on Critically Ill Patients' Outcomes

Hager AbdelNasser Hussein0 个研究点目标入组 60 人开始时间: 2023年9月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
主要终点
Complications

研究概览

简要总结

This study is aim to evaluate the effect of implementing emergency nursing protocol of obstructive anuria and oliguria on critically ill patients' outcomes.

详细描述

Obstructive anuria is defined as a total cessation of diuresis or a volume of less than 200 ml /24 hours or 0 mL/12 h. Oliguria is defined as a urine output that is less than 400 mL/24 h or less than 17 mL/h, due to unilateral or bilateral blockage of a single anatomical or functional kidney. It is rapidly the cause of acute renal failure, endangering the vital prognosis in the short term and requiring emergency treatment in a specialized environment, whatever its etiology (Afifi R, et al., 2022).

Obstructive anuria and oliguria constitutes a major cause for surgical acute kidney injury (AKI) due to several diseases as cervical cancer, urinary stone, bladder cancer, urinary tract stenosis, and iatrogenic causes. However, Obstructive anuria and oliguria management varies between each case; the treatment of choice is based on each patient's condition. We discovered that a proper management of obstructive anuria resulted in a low mortality rate as well as restoration of renal function in most patients (Wicaksono F, et al., 2021).

Anuria /Oliguria is frequently observed in the perioperative period and may be the consequence of hypovolemia and/or pain, both triggering the sympathetic nervous system, which in turn lead to activation of the renin-angiotensin-aldosterone system with ensuing oliguria. However, oliguria may also represent a warning of deteriorating renal function, especially in critically ill patients (Vincent JL and et al., 2020).

2

There are many complications from anuria and oliguria as cardiovascular complications include congestive heart failure, pulmonary edema, and hypertension, mainly as a result of salt and water retention. Gastrointestinal complications as anorexia, nausea, vomiting and gastrointestinal bleeding. Neurologic complications as confusion and seizures may develop in the course of acute oliguria. Impaired defenses and responses against infection due to uremia and inappropriate use of antibiotics may contribute to the high degree of infectious complications. Percutaneous nephrostomy is an excellent initial procedure to relieve obstruction with minimal complications. The second choice is renal dialysis for deteriorated patients (Rachid M, et al., 2020).

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Parallel
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Complications

时间窗: 1year

Electrolytes disturbances and renal failure

次要结局

未报告次要终点

研究者

发起方
Hager AbdelNasser Hussein
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Hager AbdelNasser Hussein

Mrs

Assiut University

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