Pilot study of corneal collagen cross-linking with riboflavin (C3R) with pre-operative orthokeratology

Moorfields Eye Hospital NHS Foundation Trust (UK)0 个研究点目标入组 20 人开始时间: 2008年3月27日最近更新: 2017年7月3日

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•Corneal ectasia (keratoconus, pellucid marginal degeneration or post-excimer laser corneal ectasia) in patients intolerant or with limited tolerance of contact lenses. The only other options would be INTACS or corneal grafting.

•1. Age less than 18 years or greater than 40 years
•2. Maximal K greater than 60D
•3. Minimal Oculus Pentacam pachymetry less than 400 u, to avoid the risk of endothelial damage
•4. Evidence of other corneal disease in the eye to be treated (e.g., herpes simplex keratitis)
•5. Women who are pregnant or nursing at the time of the initial treatment
•6. Presence of significant central corneal opacity
•7. Patients unwilling to not wear their rigid contact lenses in the eye to be treated for at least one month before baseline examination, and for the first six months post-operatively (this will be necessary in order to obtain accurate refraction and keratometry readings)

发起方

Moorfields Eye Hospital NHS Foundation Trust (UK)