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Prenatal treatment of Lower Urinary Tract Obstructio

Not Applicable
Completed
Conditions
Congenital bladder outflow obstruction
Neonatal Diseases
Congenital obstructive defects of renal pelvis and congenital malformations of ureter
Registration Number
ISRCTN53328556
Lead Sponsor
niversity of Birmingham (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
200
Inclusion Criteria

Mother:
1. Written informed consent given
2. Able to understand information provided (use of interpreter may be required)
3. Singleton pregnancy

Foetus:
1. Evidence of bladder outflow obstruction from ultrasound imaging
2. No major extra genitourinary anomalies present

Exclusion Criteria

Additional major structural or chromosomal anomaly

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Perinatal mortality rates and renal function at 4 - 6 weeks and 12 months measured via:<br>1. Serum creatinine<br>2. Renal ultrasound <br>3. Need for dialysis/transplant
Secondary Outcome Measures
NameTimeMethod
ot provided at time of registration
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