A pilot trial of single versus dual diuretic therapy in the intensive care unit
Phase 2
Completed
- Conditions
- critical careRenal and Urogenital - Other renal and urogenital disorders
- Registration Number
- ACTRN12623000624684
- Lead Sponsor
- Austin Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 31
Inclusion Criteria
Adults aged 18 years or above
Physician decision to administer an intravenous diuretic;
Anticipated length of stay of more than 24 hours after intervention administration
Existing intra-arterial or central venous catheter
Existing indwelling urinary catheter
Exclusion Criteria
Known allergy to furosemide or acetazolamide or other sulphonamides
known end-stage renal failure
Dose of any diuretic in the preceding 6 hours
Significant acid-base disturbance at time of enrolment (pH less than 7.25 or greater than 7.5)
Treatment with renal replacement therapy during this intensive care stay
Previously enrolled in this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method urinary output after diuretic administration[ Total urinary outcome in the 6 hours after diuretic administration while the patient is in the intensive care unit obtained from the medical record.]
- Secondary Outcome Measures
Name Time Method