A study of reducing discomfort in the eyes and nose after consuming herb powder when pollen from Cryptomeria japonica (known as sugi in Japanese) is dispersed. A double-blind, parallel group comparison study
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000039247
- Lead Sponsor
- imeQ RD inc.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 28
Not provided
1. Those who are currently receiving some types of drug and Chinese medical treatments. 2. Those with acute rhinitis, sinusitis, nasal polyp, hypertrophic rhinitis, and deviated septum. 3. Those who had undergone intranasal surgery. 4. Those with coexisting bronchial asthma. 5. Those who have or had a severe disease of the liver, heart, kidneys, gastrointestinal tract, respiratory system, endocrine, and metabolism. 6. Those who are receiving specific hyposensitization therapy. 7. Those who take oral medication or nasal spray for antihistamines or anti-allergic drugs on a daily basis. 8. Those who take Lactobacillus preparation, supplements containing Lactobacillus, or yogurt on a daily basis. 9. Those who take food products with anti-allergic effects, such as "Tian Cha" derived from Chinese Blackberry leaves and "Memehana-cha" derived from 'Benifuki' cultivar, on a daily basis. 10. Those who may have allergic reactions to test food. 11. Those who are currently taking health food (such as supplements or food products to maintain or restore health), except for those who can temporarily stop taking the above health food at the time of submission of an informed consent document and remain the same until the end of this study. 12. Those who have a past and current medical history of drug or food allergy. 13. Those who are currently participating in another clinical trial or who had participated in another clinical trial conducted within a month prior to the submission of an informed consent document. 14. Those who are currently pregnant or breastfeeding and who want to become pregnant. 15. Heavy drinkers. 16. Smokers. 17. Those who experienced a feeling of being unwell or deterioration of health condition when they had blood drawn. 18. Those who may undergo lifestyle changes (such as a long trip) during the study period. 19. Those who were determined by the principal investigator to be unsuitable for participation in this clinical trial.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method asal examination in mucosa of the inferior turbinate (swelling and color), amount of mucus fluid, and characteristics of nasal discharge. Nasal and eye symptom survey.
- Secondary Outcome Measures
Name Time Method Allergy tests for non-specific IgE in the blood, non-specific IgE (sugi or cypress), and eosinophil. The Japanese rhino-conjunctivitis quality of life questionnaire No 1 (JRQLQ No1) An antioxidant test to detect 8-hydroxy-2'- Deoxyguanosine (8-OHdG) in urine