Mild bleeding disorders caused by platelet defects

Not Applicable

• Conditions: on-malignant haematology; Haematological Disorders; Non-malignant haematology

• Registration Number: ISRCTN77951167
• Lead Sponsor: niversity of Birmingham

Brief Summary

2013 Results article in http://www.ncbi.nlm.nih.gov/pubmed/23809206 results 2014 Results article in http://www.ncbi.nlm.nih.gov/pubmed/24408324 results 2014 Results article in http://www.ncbi.nlm.nih.gov/pubmed/24618131 results 2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/25567036 results 2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/25556537 results 2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26280575 results 2017 Results article in http://www.ncbi.nlm.nih.gov/pubmed/28762630 results

Detailed Description

Not available

Study Timeline

• Study Start: 2011-04-28
• Last Update Posted: 29 April 2024
• Study Completion: 2027-02-28

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

1. Patients, aged 0 ?- 85 years, either sex
2. Diagnosed with a platelet disorder of unknown cause
3. Willing to participate and able to provide informed consent

Exclusion Criteria

1. Patients taking drugs that are known to influence platelet function, including nonsteroidal anti-inflammatory drugs (NSAIDs) including COX-2 selective anti-inflammatory drugs), aspirin, clopidogrel, dipyridamole, warfarin or acenocoumarol within 7 days of enrolment
2. Patients having undergone a major surgical procedure within 1 month of enrolment
3. Patients with chronic renal failure requiring dialysis
4. Patients with a platelet count outside the 100 000 to 450 000/µL range
5. Patients with severe anaemia (haemoglobin < 8g/dl)

Study & Design

• Study Type: Observational
• Study Design: Not specified