COMPLIANCE An Observational Study of Treatment Compliance and Quality of Life in Patients on Antihypertensive Medication

Completed

• Conditions: High Blood Pressure

• Registration Number: NCT01274494
• Lead Sponsor: AstraZeneca

Brief Summary

The aim of this multi-centre survey is to assess treatment adherence and quality of life in a Jordanian and Lebanese population newly diagnosed with hypertension or with uncontrolled essential hypertension being on antihypertensive treatment for at least 6 months.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-01-10
• Study First Submitted QC: 2011-01-10
• Study First Posted: 2011-01-11
• Study Start: 2011-05
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Status Verified: 2013-09
• Last Update Submitted: 2013-09-10
• Last Update Posted: 2013-09-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1501

Inclusion Criteria

• Patients older than 21 years of age
• Patients newly diagnosis with essential hypertension or with hypertension that is uncontrolled after being under the same antihypertensive treatment for at least 6 months (based on the criteria established by the Joint National Committee VII)
• Patients capable of providing an informed consent

Exclusion Criteria

• Patients with secondary hypertension
• Pregnant women or nursing mothers
• Patients with acute illnesses or psychiatric diagnosis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Compliance rate	6 months	Identify the percentage of subjects compliant to their antihypertensive treatment.

Secondary Outcome Measures

Name	Time	Method
Health Related Quality of Life (MINICHAL Score)	6 months	To compare and identify changes in the quality of life before and after anti-hypertensive treatment.
Type of pharmacological treatments	6 months	To identify the pharmacological treatments used by physicians in Jordan and Lebanon to treat patients newly diagnosed or with uncontrolled hypertension.
Factors affecting adherence to treatment	6 months	To identify associated factors that may alter adherence to anti-hypertensive treatment.
Compliance rate by antihypertensive regimen used	6 months	To compare treatment rate for different antihypertensive regimen used
Percentage of controlled patients	6 months	To identify the percentage of patients reaching their target blood pressure according to the JNCVII criteria.