A mechanism-based group-psychotherapy approach to aggressive behavior (MAAP) in borderline personality disorder (BPD): a multicenter randomized controlled clinical trial - MAAP

Klinik für Allgemeine Psychiatrie0 个研究点目标入组 186 人开始时间: 2023年10月31日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Outpatients with at least four diagnostic criteria of BPD fulfilled according to a structured interview, the International Personality Disorder Examination (IPDE based on DSM-5)
•Exhibit overt aggression OAS-M(1-3) = 15 and irritability OAS-M(5-6) = 6 within two weeks prior to inclusion
•live within 70km from a study centre
•Sufficient German language skill to participate in a group setting

•- Suicidality: due to the high prevalence of suicidality in patients with BPD, the possibility of initiating treatment is assessed using item 7 of the OAS-M, which captures suicidal tendencies; suicidality is assessed on an individual basis by a clinician if the score is =3
•- Acute/previous schizophrenia
•- Acute bipolar I disorder
•- Acute moderate to severe substance use disorder
•- No ability/willingness to abstain from drug/alcohol use during therapy sessions (assessed by a clinician on an individual basis)
•- History of a serious medical condition that interferes with participation in regular sessions
•- Severe cognitive impairment as measured by mini-q (IQ<70).
•- Other ongoing psychotherapy
•- Increase in current psychotropic medication or initiation of new psychotropic medication within two weeks prior to study assignment (6 weeks instead of 2 weeks for fluoxetine)
•- Ongoing criminal investigation, placement in a forensic hospital for at least 2 years, or incarceration

发起方

Klinik für Allgemeine Psychiatrie