RETHINK: a Cohort study to REconsider the Factors that INfluence StroKe Recovery.

Not Applicable

• Conditions: Ischaemic stroke; Stroke - Ischaemic

• Registration Number: ACTRN12619001059156
• Lead Sponsor: niversity of Technology Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-30
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 970

Inclusion Criteria

Ischaemic stroke cases defined in consultation with specialist neurologist and based on routine care imaging (CT and/or MRI); greater than 18 years old and have persistent symptoms of any deficit for greater than 5-7 days. Stroke is defined by standard definitions and then stratified into groups according to domains of deficit. Each recovery domain will be defined by clinical symptom items as per National Institute of Health Stroke Scale (NIHSS). Parameters include deficit symptoms persisting for greater than 5-7 days.

Exclusion Criteria

Severe illnesses i.e. palliative medical management in place, another neurological condition, seizure activity that prevent NIHSS assessment, patients unable to provide consent due to communication deficits or have no access to appropriate substitute decision maker, carer or in the case of non-English speaking case, a translator. For study subjects who agree to participate in the faecal microbiome arm, exclusion will include a history of inflammatory bowel disease or antibiotic use within 30 days of admission.

Study & Design

• Study Type: Observational
• Study Design: Not specified