NCT01626339Unknown不适用
Effect of Intravitreal Anti-Vascular Endothelial Growth Factors on Retinal Vessels Diameter
适应症
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 2
研究概览
简要总结
Patients who will be scheduled for intravitreal injection of Ranibizumab or Bevacizumab will be recruited in this prospective self-controlled trial. Fundus photography will carried out at baseline immediately before injection and at 3, 7 days and 30 days after the first injection. Using image analysis software, measurements summarized as the central retinal artery equivalent (CRAE) and central retinal vein equivalent (CRVE).
Null Hypothesis: There is no significant difference between arteriolar/venular diameter before and after injection of intravitreal ranibizumab/bevacizumab in the treated and untreated eye
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who wish and need bevacizumab or ranibizumab treatment for underlying disease
排除标准
- •History of previous systemic or ocular Anti-VEGF therapy
- •History of previous intravitreal injection with any drug
- •Intraocular pressure ≥ 22
- •History or presence of thromboembolic events
- •Un-controlled blood pressure
- •Blood donation during the previous 3 weeks
- •Relevant media opacity of the lens
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
VEGF-antagonism and Endothelial Function in Age-related Macular Degeneration (AMD)Macular DegenerationNCT00727753University of Zurich54
Unknown
不适用
The Effects of Bevacizumab and Ranibizumab on Ocular Pulse Amplitude in Neovascular Age Related Macular Degeneration (AMD)Neovascular Age Related Macular DegenerationNCT00640640Sheba Medical Center60
已完成
不适用
Investigates Improvement in Vision Following Switching From Avastin and Macugen Over to LucentisWet AMDNCT00804934Retina Institute of Hawaii100
终止
2 期
Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular DegenerationAge Related Macular DegenerationNCT00347399Asociación para Evitar la Ceguera en México25
已完成
不适用
Intravitreal Ranibizumab or Aflibercept After Bevacizumab in Diabetic Macular EdemaDiabetic Macular EdemaDiabetic RetinopathyNCT04018833Bernardete Pessoa MD40