Prospective Cohort Observational Study of Placenta Accreta Spectrum Disorders
- Conditions
- Placenta Accreta Spectrum Disorders,Previous Cesarean Section
- Registration Number
- NCT06021964
- Lead Sponsor
- Guangzhou Medical University
- Brief Summary
The incidence of placenta accreta spectrum disorders has shown an increasing trend worldwide due to the increase of cesarean section rate. Research on the outcomes of placenta accreta spectrum disorders primarily relies on retrospective analysis. The aim of this study was to establish a prospective, multicenter cohort in China in order to conduct further investigations on the clinical features, predictive capabilities, diagnostic methods, and pathogenesis of placenta accreta spectrum disorders.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- Female
- Target Recruitment
- 1000
- Pregnant women aged 18-45;
- at least one previous cesarean section ,regular antenatal examination and plan to give birth at research center
- sign informed consent
Irregular antenatal examination; Twins; Autoimmune diseases; Prepregnancy hypertension; Prepregnancy diabetes mellitus; Inheritance Sexual diseases; tumor; Abnormal liver and kidney function in early pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of placenta accreta spectrum disorders baseline
- Secondary Outcome Measures
Name Time Method Blood loss in the first 24 hours of delivery baseline Blood transfusion baseline hysterectomy baseline Preterm delivery Preterm delivery baseline Blood lost during delivery baseline
Trial Locations
- Locations (1)
Department of Obstetrics and Gynecology, Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology，The Third Affiliated Hospital of Guangzhou Medical University
🇨🇳Guangzhou, China