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The effect of pulsed light therapy on meibomian gland dysfunction patients

Not Applicable
Completed
Conditions
Diseases of the eye and adnexa
Registration Number
KCT0003051
Lead Sponsor
Yonsei University Health System, Severance Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
30
Inclusion Criteria

1.Adult over 19 years of age
2.Patient diagnosed with meibomian gland dysfunction
3.Fitzpatrick skin type I-IV
4.Those who voluntarily agreed to participate in the study

Exclusion Criteria

1.Fitzpatrick skin type V-VI
2.Sun or artificial tanning within 4 weeks prior to the study participation
3.Dermatologic condition that does not allow to receive light therapy
4.Ocular or eyelid surgery within 6 months prior to study participation
5.Ocular infection or inflammation
6.Precancerous lesion or skin cancer in the treatment area
7.Systemic infection or immunosuppressive status
8.Medical conditions associated with photosensitivity such as herpes simplex virus infection, systemic lupus erythematosis and porphyria
9.Medications which can cause photosensitivity such as isoretinoin, tetracycline, and St. John’s warts
10.Radiotherapy history within 1 year prior to study participation, or planned radiotherapy within 8 weeks from study conclusion
11.Chemotherapy history within 8 weeks prior to study participation, or planned chemotherapy within 8 weeks from study conclusion
12.Topical medication use on the treatment area or a new drug history within 3 months prior to study participation
13.Change in previous drug regimen within 3 months prior to study participation
14.Pregnant or lactating
15.Monocular
16.Those who the investigators consider inappropriate to participate in the study

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in meibomian gland function
Secondary Outcome Measures
NameTimeMethod
Change in tear cytokine;Change in corneal and conjunctival staining;Change in tear break-up time;Change in Ocular Surface Disease Index
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