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临床试验/NCT04741217
NCT04741217Unknown不适用

A Proof of Concept Study to Evaluate Aerosol Generation During Non-Invasive Positive Pressure Respiratory Procedures

Guy's and St Thomas' NHS Foundation Trust0 个研究点目标入组 10 人开始时间: 2021年3月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
10
主要终点
Characterisation of aerosolised respiratory droplets

研究概览

简要总结

Currently, a major issue within respiratory medicine is undertaking procedures that generate aerosolisation with the concern of spreading infection, such as the SARS-COV-2/COVID-19 virus. It is anecdotally reported that lung function testing and positive airways pressure devices used in clinical practice are aerosol generating procedures however the data to support this is limited. With the advent of high-speed imaging systems that can capture and quantify particle size and velocity we aim to investigate the aerosol generation in routine non-invasive positive pressure respiratory procedures.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18-80 years
  • Healthy subjects with no active medical conditions or previous pneumothorax
  • Cognitively and linguistically able to follow instructions given in English and provide informed consent

排除标准

  • Significant respiratory, cardiac or neurological conditions or previous pneumothorax
  • Smoking history greater than 10 pack years
  • Acute illness at the time of assessment
  • Allergies to latex, metals or local anaesthetic agents

结局指标

主要结局

Characterisation of aerosolised respiratory droplets

时间窗: 1 year

Performed using high-speed imaging and particle size counters

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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