A Proof of Concept Study to Evaluate Aerosol Generation During Non-Invasive Positive Pressure Respiratory Procedures
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 主要终点
- Characterisation of aerosolised respiratory droplets
研究概览
简要总结
Currently, a major issue within respiratory medicine is undertaking procedures that generate aerosolisation with the concern of spreading infection, such as the SARS-COV-2/COVID-19 virus. It is anecdotally reported that lung function testing and positive airways pressure devices used in clinical practice are aerosol generating procedures however the data to support this is limited. With the advent of high-speed imaging systems that can capture and quantify particle size and velocity we aim to investigate the aerosol generation in routine non-invasive positive pressure respiratory procedures.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-80 years
- •Healthy subjects with no active medical conditions or previous pneumothorax
- •Cognitively and linguistically able to follow instructions given in English and provide informed consent
排除标准
- •Significant respiratory, cardiac or neurological conditions or previous pneumothorax
- •Smoking history greater than 10 pack years
- •Acute illness at the time of assessment
- •Allergies to latex, metals or local anaesthetic agents
结局指标
主要结局
Characterisation of aerosolised respiratory droplets
时间窗: 1 year
Performed using high-speed imaging and particle size counters
次要结局
未报告次要终点
