The Role of Chest Electrical Impedance Tomography in the Pediatric Ventilator Weaning
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 83
- 试验地点
- 1
- 主要终点
- Correlate Electrical impedance tomography to Extubation failure
研究概览
简要总结
To correlate the data obtained by Electrical impedance tomography (EIT) during the spontaneous breathing trials (SBT) on a T-piece, in children, with failure in the trial and Extubation failure.
Observe if the EIT monitoring will be able to detect the children that will fail earlier than the SBT performed alone.
Method: A cross-sectional, prospective study to explore the potential benefits of monitoring with EIT during weaning.
详细描述
Early and successful Extubation is sometimes a difficult combination in children, since the criteria for suggesting it are often subjective and poorly defined. Electrical impedance tomography (EIT) has been developed and used clinically for more than 30 years. Interest in this technology arose from the need to monitor ventilation and pulmonary perfusion at the bedside. Because it is a non-invasive and non-radiation technology, EIT is very promising in the pediatric population. Objectives: To correlate the data obtained by the EIT during the spontaneous breathing trials (SBT) on a T-piece with failure in the trial and Extubation failure and to observe if the EIT is able to detect the children that will fail earlier than the SBT performed alone. Method: A cross-sectional, prospective study to explore the potential benefits of monitoring with EIT during weaning. Qualitative characteristics will be described using absolute and relative frequencies and the quantitative characteristics will be described using summary measures (mean, standard deviation, median, minimum and maximum). Bivariate and later multiple logistic regression analyzes will be performed to evaluate the influence of characteristics assessed on weaning failure, mainly the reduction in functional residual capacity during and after the weaning trial. For the analysis will be used the software IBM-SPSS for Windows version 20.0 and tabulation of the data will be used Microsoft Excel 2010 software. The tests will be performed with significance level of 5%.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 28 Days 至 15 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children who are on mechanical ventilation for a period of more than 24 hours, between 28 days of age and 15 years, who are admitted to the pediatric intensive care unit (ICU) of the Children's Institute in Brazil
排除标准
- •Upper Airway Obstruction
- •Diaphragmatic hernia or diaphragmatic paralysis
- •Chronic use of mechanical ventilation
- •Cyanogenic congenital heart disease
- •Primary pulmonary hypertension
- •Neuromuscular disease
- •Tracheostomy
结局指标
主要结局
Correlate Electrical impedance tomography to Extubation failure
时间窗: 48 hours
Compare data obtained by the EIT during the spontaneous breathing trial with Extubation failure
Correlate Electrical impedance tomography to spontaneous breathing trial failure
时间窗: 1 hour
Observe if Electrical impedance tomography detects children who will fail in spontaneous breathing trial (during a 1-hour T-piece) earlier than clinical criteria
次要结局
- Electrical impedance tomography Security(2 hours)
- Compare tidal volume and RR / VT index with Z-delta and RR / Z-delta(1 hour)
