Study the effect of local steroid injection in treatment of melasma
Phase 1
- Conditions
- Melasma.Chloasma
- Registration Number
- IRCT2013061813699N1
- Lead Sponsor
- Vice- chancellor for Research and technology Hamedan University of Medical Science.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 42
Inclusion Criteria
(a) patients with melasma; (b) age between 25 and 40. Exclusion criteria: (a) pregnancy; (b) atrophy in melasma lesion; (c) autoimmune disease; (d) male; (e) telangiectasia in melasma lesion; (f) using oral contraceptive
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Color of Melasma lesion. Timepoint: Fifteen and 45 days after injection. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method Atrophy in Melasma lesion. Timepoint: The first and second months after injections. Method of measurement: Observation of lesion by researcher.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the efficacy of local steroid injections in melasma treatment?
How does the effectiveness of local steroid injections compare to Kligman's formula in melasma patients?
Are there specific biomarkers that predict response to steroid therapy in facial melasma?
What are the potential adverse effects of intralesional steroid injections for melasma and how are they managed?
What combination therapies or alternative drugs are being explored alongside steroids for melasma treatment?