DRKS00009605
Completed
未知
The effect of a ketogenic diet (KD) - a very low carbohydrate and high-fat diet - without caloric restrictions on endurance capacity in healthy adults. - KetoPerformance
niversitätsklinikum Freiburg; Klinik für Innere medizin I; Hämatologie, Onkologie und Stammzelltransplantation0 sites42 target enrollmentJanuary 8, 2016
ConditionsHealthy participants
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Healthy participants
- Sponsor
- niversitätsklinikum Freiburg; Klinik für Innere medizin I; Hämatologie, Onkologie und Stammzelltransplantation
- Enrollment
- 42
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •?Age \>18 years
- •?Body mass index 19\-30 kg/m2
- •?Weight loss \<5% of body weight in the last 6 months
- •?Adequate renal function (serum creatinine \< 1\.5 X UNL \[upper normal limit] or creatinine clearance \> 50 ml/min)
- •?Adequate liver function: bilirubin \= 1\.5 x upper limit of normal (UNL) range, ALAT and/or ASAT \= 2\.5 x UNL, Alkaline Phosphatase \=5 x UNL
- •?Written informed consent
Exclusion Criteria
- •Known G6PD (glucose\-6\-phosphate dehydrogenase) deficiency
- •Diabetes mellitus undergoing therapy with insulin or oral agents
- •Kidney stones
- •Pregnant or lactating women
- •Disorders of fatty acid metabolism: carnitine deficiency (primary), carnitine palmitoyltransferase (CPT) I or II deficiency, carnitine translocase deficiency, ß\-oxidation defects, short\-chain acyl dehydrogenase deficiency (SCAD), medium\-chain acyl dehydrogenase deficiency (MCAD), long\-chain acyl dehydrogenase deficiency (LCAD), medium\-chain 3\-hydroxyacyl\-CoA deficiency, long\-chain 3\-hydroxyacyl\-CoA deficiency, pyruvate carboxylase deficiency, porphyria
Outcomes
Primary Outcomes
Not specified
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