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role of Dazzle capsule in Rheumatoid arthritis

Phase 4
Completed
Conditions
Health Condition 1: null- Rheumatoid arthritis
Registration Number
CTRI/2016/01/006572
Lead Sponsor
Vasu Research Centre
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

Presence of any four out of the following seven (Joneâ??s) criteria (according to 1987, revised criteria of American College of Rheumatology)

a. Morning stiffness: Stiffness in and around joints lasting one hour before maximal improvement (More than 6 weekâ??s duration).

b. Arthritis of three or more joints, at least three joint area, observed by scholar, having pain with soft tissue swelling or joint effusion, not just bony over growth, (more than 6 weeks duration).

c. Arthritis of hand joints, at least 1 area in wrist and hand is swollen (more than 6 weeks duration).

d. Symmetric arthritis (more than 6 weekâ??s duration).

e. Presence of Rheumatoid Nodules

f. Serum Rheumatoid factor- positive

g. Typical radiographic changes of arthritis on PA view of hand & wrist radiograph that must include erosions or unequivocal bony decalcification, localized in or adjacent to involved joints.

Exclusion Criteria

Patients who have developed complications of Rheumatoid Arthritis e.g. severe deformity of joints / bones, pleura-pericardial disease, or else.

(2) Patients with poorly controlled Hypertension or with uncontrolled Diabetes Mellitus and having a past history of Atrial Fibrillation, Acute Coronary Syndrome, Myocardial Infarction, Stroke or Severe Arrhythmia in the last 6 months.

(4) Patients on prolonged medication with corticosteroids, antidepressants, anticholinergics, etc. or any other drugs that may have an influence on the outcome of the study.

(5) H/o hypersensitivity to any of the trial drugs or their ingredients.

(6) Pregnant/lactating women.

(7) Patients having chronicity >10 years

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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