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implication of Deferoxamine in the treatment of kienbock’s disease

Phase 3
Recruiting
Conditions
Kienböck disease of adults.
Adult osteochondrosis of carpal lunate
Registration Number
IRCT2017073035382N1
Lead Sponsor
Vice Chancellor for research of Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
10
Inclusion Criteria

Radiologic Diagnosis of the Kienbock's disease by 3 hand surgeons; Age of 18 to 60 years. Lack of hematologic disorders and any disease with platelet Dysfunction; Lack of any comorbid disorders that might increase the risk of surgery including uncontrolled diabetes, cardiovascular disorders, rheumatic diseases such as rheumatoid arthritis, cancers, hepatic and renal failure and etc; Consumption of no drug which affect bone restoration such as corticosteroids.

Exclusion Criteria

New severe trauma affecting the fracture dislocation and fixation status, Incidence of severe infection which can not be controlled with antibiotics and needs surgery; Incidence of disorders needing specific drugs such as corticosteroids and chemotherapy which affect the bone repair.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical and radiologic symptoms. Timepoint: Months 3, 6 and 12 of intervention. Method of measurement: Range of Motion, Xray and MRI.
Secondary Outcome Measures
NameTimeMethod
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