Preterm Infant Multicentre Growth Study
- Conditions
- Preterm Infant
- Registration Number
- NCT03064022
- Lead Sponsor
- University of Calgary
- Brief Summary
The purpose of this study is to improve health professionals understanding of preterm infant growth patterns, and to determine if early growth patterns predict risks of adverse metabolic and cognitive outcomes.
- Detailed Description
The purpose of this study is:
To improve health professionals understanding of preterm infant growth patterns, and to determine if growth patterns (rapid early growth in the first 2 weeks of life, weight less than the 10th percentile at the time of discharge) predict risks of adverse metabolic outcomes (measured as overweight at age 3) once the following variables are controlled for: size at birth (z-score), neonatal morbidities, social determinants of health, and nutritional adequacy in the neonatal intensive care unit (NICU).
To assess diagnostic accuracy of 36-week anthropometric weight, length and head circumference \<10th and \<3rd percentiles to predict preterm infant cognitive impairment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1275
- < 32 weeks gestational age at birth
- infants who had congenital anomalies or those who died prior to discharge
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Neurodevelopment Twenty-one months of age Neurodevelopment (Bayley scale scores II and III), diagnoses of cerebral palsy, or other neurologic impairments) measured
- Secondary Outcome Measures
Name Time Method Growth patterns From birth to 50 weeks post-menstrual age Growth patterns of preterm infants relative to the Fenton growth chart
Overweight Three years of age Overweight will be defined as body mass index
Trial Locations
- Locations (2)
Cumming School of Medicine
🇨🇦Calgary, Alberta, Canada
Regina Qu'Appelle Health Region
🇨🇦Regina, Saskatchewan, Canada
Cumming School of Medicine🇨🇦Calgary, Alberta, Canada