Preterm Infant Multicentre Growth Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Preterm Infant
- Sponsor
- University of Calgary
- Enrollment
- 1275
- Locations
- 2
- Primary Endpoint
- Neurodevelopment
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The purpose of this study is to improve health professionals understanding of preterm infant growth patterns, and to determine if early growth patterns predict risks of adverse metabolic and cognitive outcomes.
Detailed Description
The purpose of this study is: To improve health professionals understanding of preterm infant growth patterns, and to determine if growth patterns (rapid early growth in the first 2 weeks of life, weight less than the 10th percentile at the time of discharge) predict risks of adverse metabolic outcomes (measured as overweight at age 3) once the following variables are controlled for: size at birth (z-score), neonatal morbidities, social determinants of health, and nutritional adequacy in the neonatal intensive care unit (NICU). To assess diagnostic accuracy of 36-week anthropometric weight, length and head circumference \<10th and \<3rd percentiles to predict preterm infant cognitive impairment.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\< 32 weeks gestational age at birth
Exclusion Criteria
- •infants who had congenital anomalies or those who died prior to discharge
Outcomes
Primary Outcomes
Neurodevelopment
Time Frame: Twenty-one months of age
Neurodevelopment (Bayley scale scores II and III), diagnoses of cerebral palsy, or other neurologic impairments) measured
Secondary Outcomes
- Growth patterns(From birth to 50 weeks post-menstrual age)
- Overweight(Three years of age)